ELI5: Explain Like I'm 5

Promoter bashing

Okay kiddo, so you know how in a music concert, there is someone who helps organize and promote the event so that people know about it and can attend?

Well, in the world of science and research, there are people called promoters who help organize and promote genes. These genes are like the musicians who perform at the concert.

However, sometimes scientists get frustrated with the promoters because they might not do their job very well. For example, they might not promote the gene enough for it to be expressed properly.

When scientists get frustrated with the promoters, they might engage in something called "promoter bashing." No, this doesn't mean they physically hit the promoters! Instead, they might try to find ways to make the promoters work better or replace them altogether.

Think of it like a musician who is not very good at promoting themselves. The concert promoter might try to find ways to help that musician get more exposure or find a better musician to perform instead.

So, promoter bashing is really just scientists trying to improve the way genes are expressed by finding ways to improve or replace the promoters.
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