Okay kiddo, so you know what a 2-dimensional object is, right? That's like a piece of paper, because it has two sides - it's flat, and you can fold it or roll it up into different shapes, but it never changes the fact that it only has two dimensions.
Now what if we had some magical paper that had four dimensions instead of just two, and we could bend and twist it in all kinds of crazy ways? That's kind of like what a 4-manifold is.
A 4-manifold is a mathematical object or space that has four dimensions, just like something that might exist in the real world but it's a bit hard to imagine or see in its full complexity - we usually have to use mathematical tools to describe it fully. It can be bent and curved in all sorts of ways, kind of like how we can bend and manipulate regular 2D paper, but with two extra directions to work with instead of just up-down and left-right.
People who study 4-manifolds try to understand all the different ways they can be bent and twisted without losing their fundamental structure or shape, kind of like how a balloon can be squeezed or stretched without losing its overall "balloon-ness". It's a really complicated area of math, but it helps us understand space and dimensions in a whole new way.