ELI5: Explain Like I'm 5

5α-Reductase

Alright, so imagine you have a special machine in your body that can change the way your hair grows and your body looks. This machine is called 5α-reductase.

Now, this machine takes a very important hormone called testosterone and changes it into another hormone called dihydrotestosterone (DHT). Testosterone is like the boss hormone in your body that helps you grow and develop into a big kid. But sometimes, you need a different type of hormone called DHT to help with some important things too.

Now, this 5α-reductase machine is found in different parts of your body, especially in your skin, hair, and some other organs. It's like a little factory working inside your body to make this special hormone.

You might wonder why we need this machine if we already have testosterone. Well, sometimes, our body needs more DHT for certain things. One important job of DHT is to help our hair grow in different places on our body, like on our face when we get older. It also helps with the growth and development of other important organs.

But, too much DHT can sometimes cause problems too. It can make your hair fall out from your head, which we call baldness. It can also make your prostate gland (a small organ near your bladder) bigger, which can cause some issues later on.

So, scientists have been studying this 5α-reductase machine to understand how it works and how it affects our body. They have even created some special medicines called 5α-reductase inhibitors that can help control the amount of DHT our body makes. These medicines can be used to treat certain issues like hair loss and problems with the prostate gland.

So, in summary, 5α-reductase is a special machine in our body that changes testosterone into another hormone called DHT. It helps with things like hair growth and the development of important organs. Scientists have discovered ways to control this machine using special medicines to treat some problems that can occur when there is too much DHT.