ELI5: Explain Like I'm 5

Alpha-latrotoxin

Alpha-latrotoxin is a really big and bad poison that comes from a spider called the black widow. Think of the black widow as a really mean spider that can make people really, really sick. Alpha-latrotoxin is like the weapon that the black widow spider uses to win fights.

When the spider wants to attack something, it will use its fangs to inject alpha-latrotoxin into the other animal. Once the poison is inside, it starts to do some really bad things. It affects the way that the body's nerves work, which are like tiny wires that run all throughout the body. These nerves help you move your arms and legs, feel things with your hands and feet, and do lots of other things that make your body work.

But alpha-latrotoxin makes the wires go crazy! It sends too many signals to your brain and makes you feel like you are in a lot of pain. It can make it hard to move, see, or even breathe. Sometimes, the poison is so bad that it can even make someone really sick or hurt them so much that they die.

So basically, alpha-latrotoxin is a really bad poison that comes from an angry and scary spider. If someone gets poisoned by it, they can get really sick and might have trouble moving or breathing. Stay away from black widow spiders and tell a grown-up if you ever see one!