ELI5: Explain Like I'm 5

Autapse

Okay kiddo, let me tell you about something called an autapse. Imagine a toy train set with a train moving around on the track. Now imagine that the train is touching the same part of the track it just passed over. This is what an autapse is - when a nerve cell (or neuron) touches itself with one of its own branches.

Neurons are special cells in our body that help us to think, feel, and move. They pass messages between each other through long branches called axons, and tiny branches called dendrites. Sometimes, however, a neuron might grow a little branch that connects back to the main branch of the same neuron. This little branch is called an autapse.

So why would a neuron do that? Well, it turns out that having an autapse can help a neuron to communicate better with itself. It's like when you talk to yourself to remember something, or when you practice something over and over again to get it right. The autapse can help the neuron to strengthen certain connections, or to filter out unnecessary noise.

Think of it like a chef who tastes his soup before serving it - he wants to make sure it's just right, and that there aren't any funny flavors in there. The autapse helps the neuron to taste its own messages and make sure they're clear and strong before sending them on to other neurons. And that's what an autapse is, in a nutshell!