ELI5: Explain Like I'm 5

Balancing selection

Balancing selection is like making sure that all your toys in your toy box get played with equally. Sometimes, when you have a lot of toys, you might like playing with one toy more than the others. But if you keep playing with that toy all the time, the other toys might get lonely and sad because they're not getting played with enough.

Balancing selection in nature is similar. It's a way to make sure that all different versions of a gene, or all different traits in a population, get a chance to be "played with" (or expressed) equally. In nature, different versions of a gene can lead to different traits in an organism, like the color of its eyes, the shape of its beak, or how resistant it is to a certain disease. Sometimes, one version of a gene might be really good for a certain environment, while another version might be better for a different environment.

But if only one version of a gene is always getting passed on to the next generation, then the other versions might start to disappear. That's where balancing selection comes in. It's like Mother Nature makes sure that all the different versions of a gene or all the different traits get a chance to be passed on, so that the population stays diverse and healthy.

There are different ways that balancing selection can happen. One way is called heterozygote advantage, which means that having two different versions of a gene (one from each parent) is better than having two identical copies. For example, in sickle-cell anemia (a disease that affects the shape of red blood cells), having one copy of the sickle cell gene and one copy of the normal gene can actually be an advantage, because it makes a person more resistant to malaria. So, even though having two copies of the sickle cell gene can cause the disease, having one copy is actually good for a person's health.

Another way that balancing selection can happen is through frequency-dependent selection. This means that the advantage of a particular trait depends on how common it is in the population. For example, if one bird species has a really long beak that's good for getting nectar from flowers, but another bird species has a short beak that's good for getting insects from tree bark, then the advantage of each beak length depends on how many birds of each species there are. If there are more birds with long beaks, then the short-beaked birds might have an advantage because they can get the insects that the long-beaked birds can't reach. So, the advantage of each beak length depends on the frequency (or number) of birds with each length.

Overall, balancing selection is an important way to keep populations diverse and healthy. It's like making sure that all the toys in your toy box get played with, so that none of them get left out and sad.