ELI5: Explain Like I'm 5

Conformational entropy

Conformational entropy is a way of measuring how much energy is stored in the ability of molecules to move. Imagine if you had a toy that had lots of different parts that could be moved around. If someone asked what the energy of the toy was, the answer would include not only the energy locked in the parts of the toy, but also the energy the toy has because its parts can be moved to create different shapes. Conformational entropy is like this. It measures the energy stored in a molecule because different parts of it can move and create different shapes. This energy is important because it helps determine how easily a reaction will occur.