Okay kiddo, imagine if you and your friends came from different places and you all had different traditions and ways of doing things. In grown-up talk, we call these differences "cultures". A cultural region is a big area where lots of people share similar cultures and ways of doing things.
For example, in the United States, the South is a cultural region where people have a certain accent, eat certain foods like fried chicken and biscuits, and have traditions like celebrating Mardi Gras. Another example is the Mediterranean cultural region, which includes countries like Italy, Greece, and Spain, where people eat similar foods like pasta and olives, and have similar types of buildings and architecture.
So, a cultural region is like a big area where a lot of people have similar traditions, languages, and ways of life that make them different from people in other areas. It's kind of like having a big group of friends with a lot in common!