ELI5: Explain Like I'm 5

Dynamic combinatorial chemistry

Okay kiddo, let's imagine that you have a toy box full of different toys, each of which can be taken apart and put back together in different ways. That's kind of like what dynamic combinatorial chemistry is all about.

In the world of chemistry, scientists have figured out how to make certain molecules that can combine in different ways to form new molecules. These groups of molecules are called "libraries" because they contain lots of different combinations.

Scientists can use special techniques to make these libraries "dynamic," which means that the substances in them are constantly changing and rearranging themselves. Just like your toys in the toy box.

The idea behind this is that by constantly shuffling the pieces around, eventually certain combinations will form that are useful for different things. Scientists can then isolate those combinations and use them for specific purposes.

Think of it like taking the different pieces of a puzzle and constantly mixing them up until you find the perfect combination to create a beautiful picture.

So, in short, dynamic combinatorial chemistry is a technique that allows scientists to create a bunch of different chemical combinations and then watch as they rearrange themselves, in hopes of finding new useful substances.