ELI5: Explain Like I'm 5

ETV6-NTRK3 gene fusion

Okay kiddo, so you know how your body is made up of tiny little things called cells? And inside those cells are things called genes. Genes are like little instructions that tell your body what to do and how to grow.

Sometimes, something funny happens with those genes. Sometimes, they join together when they're not supposed to. It's like if two puzzle pieces that don't go together somehow stick together.

When that happens to the ETV6 and the NTRK3 genes, we call it the ETV6-NTRK3 gene fusion. It's kind of like the two genes become one big instruction that tells the body to make a different kind of protein.

Sometimes, this protein can be bad and can cause cancer. But don't worry, doctors and scientists are working really hard to figure out how to stop it from happening and to help people who have it.