ELI5: Explain Like I'm 5

Electron capture dissociation

Imagine you have two Lego blocks. The first block is a blue one with a red button on it, and the second block is a yellow one with a green button on it. When you push the red button on the blue block, it makes a little explosion that separates the blue block into smaller pieces. Electron capture dissociation is kind of like pushing a button on a Lego block, but instead of breaking a toy apart, it breaks apart really small things called molecules.

Molecules are made up of atoms, which are like tiny Lego blocks themselves. Some molecules have very important jobs in our bodies, like protein molecules that help our cells do their jobs. But sometimes these molecules can get damaged and stop working, and we need a way to break them down into smaller pieces so our bodies can get rid of them.

That's where electron capture dissociation comes in. Instead of using a button, we use a type of energy called electrons. Electrons are like tiny little balls that go really fast and can move around inside atoms and molecules. When we use electron capture dissociation, we shoot some electrons at the molecule we want to break apart.

The electrons push and pull on the atoms in the molecule, kind of like shaking up a Lego tower. This shaking can break the chemical bonds that hold the molecule together, and it starts to fall apart into smaller pieces. These smaller pieces can be easier for our bodies to get rid of, kind of like breaking a Lego tower into smaller pieces to put away in a toy box.

So, electron capture dissociation is a way to break apart molecules using little balls called electrons, kind of like pushing a button on a Lego block to make it explode into smaller pieces. It can help us get rid of damaged molecules in our bodies that could hurt us if they stuck around for too long.