ELI5: Explain Like I'm 5

Epimerization

Alright, kiddo. Epimerization is when something changes to look almost the same, but it's actually different.

Let's say you have two blocks, one blue and one red. If you switch the sides of the blocks, so that the blue one is where the red one was and vice versa, they still both look like blocks, but they're not the same anymore.

In the same way, epimerization happens in molecules. Let's say you have a molecule called glucose. It's a sugar that our bodies use for energy. Now, glucose has a sister molecule called galactose. They look almost identical, except for one little difference. At one spot in the molecule, glucose has a part that sticks out one way, and galactose has a part that sticks out the other way. It's like if one of your hands was a mirror image of the other hand. They both look like hands but if you try to put your left hand in a right-handed glove, it won't fit quite right.

So, even though glucose and galactose look really similar, they're actually different molecules because of that one little difference in how they're shaped. That difference is because of epimerization.

Does that help you understand, kiddo?