FLP-FRT recombination
FLP-FRT recombination is like playing with Legos. Imagine you have two piles of Legos with different colors and shapes, and you want to make something new by combining them.
In your left hand, you have a pile of red Legos with some special yellow pieces mixed in. These yellow pieces are called FRT sites.
In your right hand, you have a pile of blue Legos with a special green piece mixed in. This green piece is called FLP.
Now, you take your red Lego pile and build a small tower using the yellow FRT pieces as the base.
Next, you take the blue pile and add the green FLP piece to the tower.
Magically, the tower breaks apart and then reassembles itself with some of the blue Legos now swapped with some of the red Legos. This is called recombination.
FLP-FRT recombination is a bit like this Legos game, but instead of Legos, we are working with DNA. The FRT sites act like special markers, and the FLP enzyme is a bit like a key that can unlock and recombine those markers.
Scientists can use FLP-FRT recombination to manipulate DNA in different ways, such as deleting or inserting specific genes into a cell's genetic code. It's like Lego engineering for scientists!
In your left hand, you have a pile of red Legos with some special yellow pieces mixed in. These yellow pieces are called FRT sites.
In your right hand, you have a pile of blue Legos with a special green piece mixed in. This green piece is called FLP.
Now, you take your red Lego pile and build a small tower using the yellow FRT pieces as the base.
Next, you take the blue pile and add the green FLP piece to the tower.
Magically, the tower breaks apart and then reassembles itself with some of the blue Legos now swapped with some of the red Legos. This is called recombination.
FLP-FRT recombination is a bit like this Legos game, but instead of Legos, we are working with DNA. The FRT sites act like special markers, and the FLP enzyme is a bit like a key that can unlock and recombine those markers.
Scientists can use FLP-FRT recombination to manipulate DNA in different ways, such as deleting or inserting specific genes into a cell's genetic code. It's like Lego engineering for scientists!