Okay, kiddo! Imagine you and your friend want to build a Lego tower together. You both have different kinds of Lego blocks - your friend has green blocks and you have red blocks. You can build a tower separately with just red blocks, and your friend can build a tower separately with just green blocks, but to build a big tower together, you need to work together and use both kinds of blocks.
In the same way, a heterotetramer is a big special protein that is made up of four smaller protein parts, but those parts are not all the same. Each part is different, kind of like the different colored Lego blocks. These protein parts might be called subunits, just like you and your friend have different sets of Lego blocks.
But, even though each subunit is different, they all work together to make a special big protein that does a really important job in our bodies. Just like you and your friend working together can build a bigger tower than you could build separately with your own Lego blocks!
So, a heterotetramer is like a big special protein made of different kinds of smaller protein parts, all working together to do an important job.