ELI5: Explain Like I'm 5

Isograft

Imagine you have a toy that you really love and you want to share it with your best friend, but you don't want them to have their own version of the toy. So, you decide to give them your exact same toy to play with. This is kind of like how an isograft works.

An isograft is when doctors take tissue, like skin or bones, from one person and transplant it into another person who has the same genetic makeup. This means that the tissue being transplanted is an exact match to the person receiving it.

Just like how your toy is the same as your friend's now, the transplanted tissue is the same as the tissue in the recipient's body. And because the tissue is an exact match, there is no risk of rejection or complications. This makes an isograft a very helpful transplant option for things like burn victims or cancer patients who need new skin or bone tissue.

So, to sum it up, an isograft is like sharing a toy with your best friend, but the toy is actually tissue being transplanted from one person to another who have the same genetic makeup. It's a perfect match that helps people in need of new tissue without any complications.