ELI5: Explain Like I'm 5

MAPK/ERK pathway

The mapk/erk pathway is like a choose-your-own-adventure book for cells. Imagine your cells are little book characters trying to figure out what to do next. The mapk/erk pathway helps them make decisions on things like whether or not to grow, move, or divide.

The pathway works by using special molecules called proteins to send signals from the outside of the cell to the inside. Think of the proteins like the postman delivering a letter to your mailbox. Once the signal is received, the cell can make a decision on what action to take.

The mapk/erk pathway has three main parts: the receptor, the protein chain, and the nucleus.

The receptor is like a doorbell for the cell. When a signal molecule comes to the cell and binds to the receptor, it’s like someone ringing the doorbell and letting you know that they’re there.

The protein chain is like a telephone game. Once the signal has been received by the receptor, it’s like the message has been relayed to the first person in line. This person then tells the next person in line, and so on, until the message gets to the end.

The nucleus is like the brain of the cell. Once the message has traveled through the protein chain, it’s like the message has been received by the brain. The brain then decides what action the cell should take.

Overall, the mapk/erk pathway is like a guidebook for cells to make decisions on what they should do next. By using proteins to send signals, the cell can receive information on what’s going on outside and decide what to do inside.