ELI5: Explain Like I'm 5

Medical genetics of Ashkenazi Jews

Okay kiddo, let’s start by talking about genes. Our bodies are made up of lots of tiny things called cells, and inside those cells are genes. Genes are like recipes that tell our bodies how to work and what to do.

Now, some groups of people have different genes than others. One group of people that has different genes is called Ashkenazi Jews. Ashkenazi Jews are people who have ancestors from certain parts of Europe, like Poland, Germany, and Russia.

These different genes can sometimes impact a person’s health. For example, Ashkenazi Jews are more likely to have certain genetic disorders, like Tay-Sachs disease or Gaucher disease. This is because these genes were more common in the families of Ashkenazi Jews a long time ago.

Doctors can use something called genetic testing to find out if someone has one of these genetic disorders. They do this by taking a small sample of blood or saliva from the person, which has their genes in it. Then, they can look at the genes and see if there are any differences that might cause a health problem.

The good news is that if doctors find out that someone has one of these genetic disorders, there are things they can do to help. Sometimes they can give medicine that can help with the symptoms, or give advice on how to live a healthy life with the disorder.

So, while it’s true that Ashkenazi Jews have some different genes that can sometimes cause health problems, it’s important to remember that there are lots of ways to keep ourselves healthy and happy!