ELI5: Explain Like I'm 5

Prolongation

Okay kiddo, so sometimes when people take medicine, they need to be careful because some medicines can affect the way the heart works. One way the heart works is by something called electrical signals, kind of like when you turn on a light switch to make the light turn on.

Now sometimes, some medicines can mess up these electrical signals and cause problems with the heart beating correctly. This is where prolongation comes in. Prolongation means that the time it takes for the heart electrical signal to go from one place to another takes longer than it should.

Imagine if you're playing a game of telephone (where you whisper a message to someone and they whisper it to the next person, and so on). If it takes a really long time for the message to get to the last person, it can cause problems because the message gets messed up.

The same thing happens in the heart. If the electrical signal takes too long to get to where it needs to go, the heart might not beat properly, and that can cause sickness or even death.

So when doctors talk about "prolongation," they mean that they're watching carefully to make sure the medicine isn't messing up the electrical signals in someone's heart. It's like they're playing a very important game of telephone just with the heart, to make sure everything is working properly.