Okay kiddo, let's talk about runs of homozygosity!
Picture a puzzle with many tiny pieces. These pieces represent our genes. Our genes are what make us who we are, like our hair color or how tall we will be. When we inherit genes from our parents, we get one copy of each gene from each parent.
Sometimes, in a person's genetic makeup, they may inherit the same gene from both parents. This is called homozygosity. If this happens with several genes in a row, it creates what scientists call runs of homozygosity (ROH).
But why do scientists care about this? Well, ROH can happen if two close relatives have children together, such as cousins. If these children have ROH, it could increase their chances of having certain health problems. Plus, scientists can use ROH to study how different populations are related to each other.
So, in short, runs of homozygosity are when someone inherits the same gene from both parents, and scientists use this information to learn more about health and relationships between populations.