ELI5: Explain Like I'm 5

SULT2B1

Okay kiddo, let's start with some background information first. So, our body is made up of many different parts called organs, and each organ has a different job to do. Some organs produce chemicals called hormones, which help our body do things like grow, develop, and keep everything in balance.

Now, one hormone that our body makes is called dehydroepiandrosterone sulfate, or DHEA-S for short. This hormone is made in an organ called the adrenal gland, which sits on top of our kidneys. DHEA-S plays an important role in things like immune system function, bone health, and mood regulation.

But, our body can't use DHEA-S on its own - it needs to be converted into another hormone called estrogen or androgen. And, this is where sulphotransferase 2B1 (SULT2B1) comes in.

SULT2B1 is an enzyme that helps convert DHEA-S into either estrogen or androgen, depending on what the body needs. This process is important because estrogen and androgen also have important roles in our body, like regulating our reproductive system and building muscle mass.

So, in summary, SULT2B1 is an enzyme in our body that helps convert a hormone called DHEA-S into either estrogen or androgen, depending on what our body needs.