ELI5: Explain Like I'm 5

Serial dilution

Okay, let me explain what a serial dilution is just like I would explain it to a 5-year-old!

Imagine you have a cup of juice and you want to make it weaker by adding water. You pour half of the juice into another cup, and then you add water to each of the cups so they're half full. You now have two cups of juice, but they're weaker than the original cup. You can do this again - pour half of one of the cups into another cup, and then add water so both cups are half full. You will end up with four cups of juice, but they are even weaker than before.

This is kind of like what happens in a serial dilution. Instead of juice, we have a liquid with some kind of substance in it that we want to measure. We start with a certain amount of the liquid, and then we add more liquid to it to make it weaker. We can do this multiple times, each time making the liquid weaker and weaker.

The reason we do this is to be able to measure how much of the substance is in the liquid. If the liquid is too strong, we might not be able to measure it accurately. But if we keep making it weaker with each dilution, eventually we'll reach a point where we can measure it accurately.

So in summary, a serial dilution is when we repeatedly add more liquid to a liquid with a substance in it to make it weaker, so that we can measure the amount of the substance more accurately.
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