ELI5: Explain Like I'm 5

Surface plasmon resonance microscopy

Imagine you have a toy car that you're trying to race down a track. You want to know how fast it's going, so you use a special sensor that can detect the car's movements as it drives by. This sensor uses something called surface plasmon resonance to measure the speed of the car.

Now, instead of a toy car, let's imagine we're looking at tiny particles that are too small for us to see with our eyes. We still want to know how they're moving, but we need a special tool to help us. That's where surface plasmon resonance microscopy comes in.

Surface plasmon resonance microscopy uses a tiny sensor that's similar to the one we used to measure the speed of the toy car. This sensor is so small that it can detect the movements of particles on a microscopic scale.

Here's how it works: the sensor is made of gold or silver nanoparticles that are arranged in a special pattern. When light is shone on these particles, something called a plasmon is created. Plasmons are like ripples in a pond, but they happen on a much smaller scale.

When particles come near the sensor, they disturb the plasmons, causing them to change in a very specific way. This change can be measured and used to determine the properties of the particles that are nearby.

So, surface plasmon resonance microscopy is like a special microscope that uses plasmons and sensors to detect the movements and properties of tiny particles that are too small for us to see on our own.