Periodic systems of small molecules are like puzzles you solve with different kinds of pieces. All the pieces can be put together to form a big picture. For example, you might have a bunch of small atoms like oxygen, nitrogen, and carbon, and you can fit them together to form molecules like water or ammonia. Each of these molecules has specific properties - like how they interact with other molecules - that help us understand how things work. With periodic systems, we can figure out what'll happen when two or more molecules get together. This is helpful for figuring out things like how our bodies work, how different chemicals interact, and how to put together materials to make things.