Bioisostere

Okay kiddo, bioisostere is kind of like when your mom asks if you want an apple or a banana for a snack. Even though they're different fruits, they both have similar properties when it comes to giving you energy and nutrition.

In a similar way, scientists use bioisostere to find different molecules that can have similar effects in our bodies. They look for molecules that have similar structures and shapes, but may have different atoms or groups of atoms. These similar molecules can be used in place of each other to make new drugs or improve old ones.

Think of it like a puzzle: sometimes you can swap one puzzle piece for another and the picture still looks the same. Scientists use bioisostere to find puzzle pieces that can fit in the same spot and still make the same picture, but might act a little differently in our bodies.

This helps scientists make better drugs that work just as well as the old ones, but might have fewer side effects or be easier to make. So, bioisostere is like finding different fruits that are equally healthy, or finding different puzzle pieces that still make the same picture.