Callus (cell biology)

Imagine you have a really rough spot on your skin, usually on your feet, because you play outside a lot or wear shoes that rub in the same spot. This rough spot is called a callus.

A callus is like a small pile of bricks that your skin builds up to protect itself. The bricks in a callus are made up of skin cells called keratinocytes. These cells divide and multiply really quickly in response to the stress or pressure on your skin.

When your skin builds up a callus, it's trying to protect itself from that stress or pressure. But the callus is also stiff and rigid, so it can make it hard to move or flex that part of your body. That's why it's important to take care of your skin and prevent calluses from building up.

So, calluses are a way your skin protects itself from stress or pressure, but they can also be uncomfortable and limit your movement. It's best to try and prevent them from forming in the first place.