ELI5: Explain Like I'm 5

Chiral resolution

Okay, kiddo, so when we talk about chiral resolution we're talking about something called chirality. Chirality is like having a left hand and a right hand, they are the same, but they are different, and they can't fit into the same glove.

Now let's imagine we have two molecules that are chiral, they look almost exactly the same, but they are like those hands, they have a mirror image that is not exactly the same. Scientists want to be able to separate these two molecules, but it's very hard to do it because they are so similar.

That's where chiral resolution comes in! Scientists can use a special technique to separate the two molecules by using a kind of filter that only lets one type of the molecule pass through. It's almost like a strainer, but instead of separating big pieces from small pieces, it separates left-handed molecules from right-handed molecules.

This is important because sometimes one of these chiral molecules can do good things for us, like curing a disease, but the other molecule can do bad things, like causing side effects. So, scientists need to be able to tell them apart and make sure they only use the good one.

And that, my dear, is how chiral resolution works!