ELI5: Explain Like I'm 5

Crosslinking of DNA

Imagine that DNA is like a long ladder with two sides (or strands). These strands are held together by rungs which are like little connecting pieces. Sometimes, these rungs can get damaged or broken. This can cause problems for the cell because it needs the DNA to work properly.

Crosslinking is like fixing the broken rungs in the ladder. It brings together two different sections of the DNA molecule to make it stronger and more stable. It’s like putting glue between the rungs to hold them together.

Scientists can use crosslinking to study DNA and see how it works. They can also use it to design new medicines or treatments for diseases that affect DNA. Just like how building blocks fit together to make a tower, DNA can be crosslinked to help it stay strong and healthy.