When we touch things with our hands, we feel something called "hand feel." Hand feel is how something feels when we touch it. For example, if we touch a fluffy pillow it feels soft and squishy in our hands. Or if we touch a prickly cactus it feels rough and pointy in our hands.
Hand feel can be affected by things like texture, weight, temperature, and moisture. For example, we might think a smooth piece of metal feels cold because it's not holding any heat, but a fuzzy blanket might feel warm because it's holding onto our body heat.
When designers and manufacturers talk about hand feel, they're usually talking about how products feel to the touch. They might try to make a shirt feel soft and comfortable or make a plastic toy feel sturdy and durable.
So, hand feel is basically how something feels when we touch it with our hands. It can be affected by all sorts of things and is important to people who make products that we use every day.