Haplogroup E-m215 is a group of people who share a common ancestor many, many generations ago. The way scientists can figure out if people with similar DNA are related is by studying what's called the Y chromosome. This chromosome can only be passed down from men to their sons, so it's like a family tree just for the dads in the family.
Now, haplogroup E-m215 is like a branch on that family tree. It means that a long, long time ago, there was a man who lived and had a mutation on his Y chromosome. This mutation was passed down to his sons, and their sons, and so on until we have a group of people today who still have that same mutation.
Think of it like a special club that you can only join if your dad's dad's dad's dad's dad, and so on, was part of that club. That's what makes this group special- they all have that same mutation on the Y chromosome, which proves that they're related way back in history.