So, you know how our body has a kind of network called nerves that help us move and feel things? Sometimes, people can have a problem with these nerves that make it hard for them to do everyday things like walking, picking things up, and feeling things like hot and cold.
When someone has hereditary motor and sensory neuropathy with proximal dominance, it means that this problem with nerves runs in their family, and it affects the nerves that are closer to their body's center, like in their arms and legs. This can make it hard for them to use their muscles and feel things in these areas.
It's like if you had a toy car with wires that make it go and a remote that makes it go forward or backward. If the wires aren't working right or the remote is broken, it's hard to make the car move the way you want it to. In the same way, when someone has hereditary motor and sensory neuropathy with proximal dominance, the wires (nerves) that are supposed to help their muscles move and feel things aren't working right, so they might have trouble doing the things they want to do.