High-dose estrogen is when doctors give someone who needs it a lot of a certain hormone called estrogen. Estrogen is a hormone that is usually found in girls and women. It is what makes them grow and develop into adults. High-dose estrogen can help treat different kinds of medical problems, like some types of cancer.
But sometimes, high-dose estrogen can also have side effects. Just like too much candy can make a kid feel sick, too much estrogen can make someone feel sick too. Some side effects can include headaches, feeling tired, and some people might feel like they have the flu.
That's why it is very important to talk to a doctor and only use high-dose estrogen when it is needed and under their care.