Okay kiddo, so when something is irradiated, it means it is exposed to a special kind of energy that can kill germs (like tiny, invisible, yucky things that make us sick).
Mail is something we send to each other in envelopes, and sometimes people are worried that the mail might have germs on it.
So, in some special cases, officials might decide to use machines that send out this special energy called radiation to kill any germs on the mail. This is called irradiating the mail.
After the mail is irradiated, it should be safe to touch and doesn't have as many germs on it. This helps keep people healthy and prevents the spread of diseases through the mail.