Left-handed tuning is when people who are left-handed play musical instruments that are typically designed for right-handed people. This means that the strings on guitars, for example, are usually ordered and tuned so that the highest-pitched string is on the top and the lowest-pitched string is on the bottom. However, left-handed players might find this arrangement uncomfortable or even impossible to play.
To make it easier for left-handers to play instruments, a few changes can be made. One option is to simply flip the guitar upside-down so that the strings are reversed, with the lowest-pitched string now on top. This might make it more comfortable to play chords and reach the strings with the left hand. However, this approach can cause problems with the instrument's bridge, which may need to be adjusted to properly accommodate the new string configuration.
Another option is to restring the guitar completely so that the strings themselves are in the reverse order. This means that the lowest-pitched string (usually an E) is still on the bottom, but it's now on the opposite side of the guitar. This approach avoids some of the complications of flipping the guitar, but it can also require adjustments to the instrument's nut and bridge.
These same principles can apply to other instruments besides guitars, such as banjos and ukuleles. Ultimately, left-handed tuning is all about finding a way to make it easier and more comfortable for left-handed people to play music.