ELI5: Explain Like I'm 5

Mouse models of colorectal and intestinal cancer

Okay, so imagine your body is like a big city, and each part of your body is like a neighborhood with lots of different buildings and people living and working there. Your intestines are like a big highway that runs through the city, helping to move things around and keep everything running smoothly.

Sometimes, bad things can happen in your intestines that can make people sick. One of these things is called colorectal cancer, which is when cells in your intestines start growing in a way that they're not supposed to. This can make people really sick and even be life-threatening if it's not treated.

To help researchers understand how colorectal cancer works and how they can stop it, they use something called mouse models. This means they create special mice in a lab that have some of the same problems as people with colorectal cancer.

The mice are specially bred to have changes in their genes that make them more likely to get colorectal cancer. Then, researchers can study these mice to learn more about how the disease develops and how to treat it.

So basically, mouse models of colorectal and intestinal cancer are like little mouse versions of people with the disease that scientists can use to figure out how to fight it off and make people healthier.
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