So kiddo, have you ever heard of painkillers? They are medicines that make your hurting go away. But some of them are very strong and can make you feel sleepy or woozy. These strong ones are called opioids.
Now, opioidergic means something that has to do with opioids in your body. When you take an opioid painkiller, it goes into your body and attaches to special places called receptors. These receptors send a message to your brain that says "hey, pain go away now".
But sometimes, taking opioids can cause problems. They can make you feel too sleepy or even stop you from breathing if you take too much. That's why it's important to only take medicines that a grownup gives you and to follow the instructions carefully.
Scientists study opioidergic things to learn more about how these medicines work in the body and how to make them safer. They want to help people feel better without causing harm.