Okay kiddo, imagine you have some really tiny things called molecules. Some of these molecules have a special part called a proton. Remember that like a magnet, protons have a plus (+) charge.
Now, let's bring in some other things called acids and bases. Acids are like sour lemon juice, and bases are like baking soda. They react with molecules in different ways. When an acid meets a molecule that has a proton, it can snatch that proton away from the molecule. This is called protonation.
So, imagine a molecule with a proton, it's like it has a little flag waving around that says "come get me acids!" When an acid comes along, it snatches up the proton and now the molecule doesn't have that little flag anymore. It's been protonated!
When a molecule gets protonated, it changes in all kinds of ways. It might get a little more positive or it might have a different shape. This protonation reaction can be really important in chemistry and biology because it can change the way molecules behave and interact with each other.
So that's protonation, kiddo! It's when an acid takes away a proton from a molecule and changes it in some way.