ELI5: Explain Like I'm 5

SWAP protein domain

Okay kiddo, so proteins are like tiny machines in our bodies that do different jobs. They are made up of smaller parts called domains, which are like different tools a machine might have.

Now, sometimes scientists might want to take one tool (or domain) from one protein and put it onto a different protein. It's like taking a hammer from one toolbox and adding it to another toolbox.

This process is called a swap protein domain and it can be really helpful for making new proteins that can do new jobs. Just like how adding a hammer to a toolbox can help you build something new.

Scientists are really good at figuring out how to do these swaps, kind of like how you might know how to switch the wheels on your toy cars to make a new car. Then they can study the new proteins with the swapped domains to see what new things they can do.

So that's the basic idea of a swap protein domain - taking a tool from one protein and putting it onto another protein to make something new and interesting!