ELI5: Explain Like I'm 5

Single-cell transcriptomics

Imagine you have a bunch of tiny little creatures in your body called cells. Each cell has its own special job to do, like helping you breathe, hear, see, or move. Scientists want to know more about what each cell is doing, so they use a special tool called single-cell transcriptomics.

When scientists use single-cell transcriptomics, they look at each cell one at a time to see which genes are turned on or off. Genes are like tiny little instruction manuals inside your cells that tell them what to do. By looking at which genes are being used, scientists can figure out what each cell is doing.

The process of single-cell transcriptomics is like taking a really close-up picture of each cell and reading its instruction manual. Scientists can then compare all the pictures and instruction manuals to figure out how all the different cells in your body work together. This helps them understand how diseases happen and how to make better medicines to treat them.

So, single-cell transcriptomics helps scientists study what each tiny little creature in your body is doing by taking a really close-up picture and reading its instruction manual. Cool, huh?