Splice variant analysis is like playing with Legos. You know how you can build different things with Legos by connecting them in different ways? Well, our bodies have something like Legos called genes, and these genes give instructions on how our bodies should work.
Now, genes are made up of something called DNA, which is like a special code that tells our body what to do. Imagine it like a very long recipe book with instructions for making different parts of our body. But, the interesting thing is that sometimes when our body wants to use a gene's instructions, it can skip or add pieces of it in different ways like Legos.
This process is called "splicing." It's a bit like if you take a recipe for chocolate cake but decide to add peanut butter to it. You're not changing the main recipe, just making a few modifications.
Scientists can study these "spliced" genes to learn more about how our body works. They can use special tools to find out which parts of the gene are being used and which are being skipped over. They can then compare the different versions of a gene and try to figure out why our body might use one version over another.
This information can be really important in medical research, because sometimes changes in genes can cause diseases or other health problems. By studying how genes are spliced, scientists can learn more about these diseases and how to treat them.