ELI5: Explain Like I'm 5

Untranslated region

Okay kiddo, have you ever read a book? Every book has a title, an introduction, and then the rest of the story, right? Well, a similar thing happens in our cells when they make proteins.

When our cells make proteins, they have to read a recipe called RNA that tells them how to make the protein. This recipe is made up of different parts, just like a book. One of the parts is the untranslated region - or UTR for short.

The UTR is the introduction of the RNA book. It's the part of the recipe that comes before the actual instructions for making the protein. The UTR helps the cell know when to start and stop making the protein. It's like a sign that says, "Hey cell, pay attention, the recipe for the protein starts now!"

But unlike the rest of the recipe, the UTR doesn't get translated into a protein. It's just there to help the cell make the protein correctly. So, think of it like the UTR is the title and introduction of a recipe book, it helps you understand what you're about to cook but you don't eat the title or introduction, you use it to make sure you have all the right ingredients and know what to do.

I hope that helps you understand what an untranslated region is, kiddo!