ELI5: Explain Like I'm 5

Β-lactamase inhibitor

Okay kiddo, let me explain what a β-lactamase inhibitor is. First, let's start with the word "β-lactamase." This is a type of enzyme that some bacteria have in their little bodies that lets them break down a type of medicine called β-lactam antibiotics. These antibiotics are helpful because they can kill harmful bacteria that cause infections in our bodies.

But, some bacteria have evolved to produce the β-lactamase enzyme that destroys these antibiotics before they can do their job. This can be a big problem because then the antibiotics won't work and the infection can get worse.

That's where β-lactamase inhibitors come in. They are like special helpers that team up with the β-lactam antibiotics to fight off the bacterial infection. The inhibitors block the bacteria's β-lactamase enzyme, which keeps the antibiotic from being destroyed. This allows the antibiotic to kill the harmful bacteria and get rid of the infection in our bodies.

So, think of the β-lactamase inhibitor as the hero that helps the medicine work better and defeat the bad guys (bacteria) in our bodies.