ELI5: Explain Like I'm 5

AIDS fatigue

AIDS is a disease that makes people very sick by attacking their immune system, which is the system in the body that helps fight off bad germs and viruses. When someone has AIDS, their body can have a hard time fighting off illnesses, which can make them feel really tired and weak. This tiredness is called AIDS fatigue.

Imagine you have a superhero inside your body that helps keep you healthy. When you get sick, this superhero fights the bad germs and helps you get better. When someone gets AIDS, it’s like the superhero inside their body gets really tired and weak. He’s still trying to fight off the bad germs and viruses, but his powers are not as strong as they used to be. This makes it harder for your body to fight off illnesses, so you can feel really tired and run down all the time. You might not have as much energy as you used to, and it may be harder to do things you enjoy.