ELI5: Explain Like I'm 5

Bcl-2

Okay, imagine you have these little soldiers in your body called cells, and they have a very important job of fighting off any bad guys that might try to make you sick. But sometimes, these soldiers get a bit confused and start attacking the good guys, or they don't know when it's time to stop fighting and they keep going, which can cause a lot of damage.

Now, imagine if there was a special soldier that could help control these confused soldiers and tell them when to stop fighting. This special soldier is called bcl-2. It's like the boss of the soldiers' team, and its job is to make sure they're all working in harmony and not causing any unnecessary damage.

But sometimes, the bad guys are very sneaky and find ways to block bcl-2 from doing its job. When this happens, the confused soldiers keep fighting and causing damage, and that's when someone can get really sick. Researchers are trying to find ways to help bcl-2 do its job better and ensure our soldiers are always working together to keep us healthy.