ELI5: Explain Like I'm 5

Noxa

So, imagine you have a bodyguard who helps protect you from bad guys. Your bodyguard is like your "noxa" - it helps your body fight off bad things that might try to harm you.

"Noxa" is a scientific term that describes things that can harm your body's cells, like toxins, radiation or other harmful molecules. When the body is exposed to these things, it triggers a defense mechanism called apoptosis, which is basically the body's way of getting rid of damaged cells.

When there is too much noxa, the body's defense system can become overwhelmed, and this can lead to diseases like cancer. Scientists are trying to better understand how noxa works so they can develop better ways to protect our bodies from these harmful things.