ELI5: Explain Like I'm 5

Hsp90 cis-regulatory element

Okay, kiddo, let me tell you about Hsp90 and its cis-regulatory element.

So, first let's talk about Hsp90. It's a protein that's really important in our body because it helps other proteins work properly. Think of it like a helper for other proteins. Hsp90 is like a superhero that saves the day by making sure other proteins are doing their job and not causing any trouble.

Now, let's talk about the "cis-regulatory element" part. That's a fancy way of saying a piece of DNA that controls when and where a gene gets turned on or off. When we say "cis", it means it's in the same molecule of DNA as the gene itself. So, the cis-regulatory element for Hsp90 is a little piece of DNA that tells our body when to turn on the Hsp90 gene and make more of that protein.

Imagine a toy car with a remote control. That remote control is like the cis-regulatory element, and it tells the car when to move and in what direction. The toy car won't move without the signal from the remote, and Hsp90 won't be made without the signal from the cis-regulatory element.

So, why is all of this important? Well, if the cis-regulatory element for Hsp90 isn't working properly, then our body might not make enough of that superhero protein to help the other proteins do their job. That can cause trouble and lead to diseases like cancer.

So, scientists study Hsp90 and its cis-regulatory element to learn more about how our body works and how we can keep it healthy. That's why they use big words like "cis-regulatory element", even though they might sound a little scary at first.