An isogram is a funny word that means a word or phrase that has every letter in it used only once. Have you ever played the game Scrabble or done a word puzzle where you have to find words using letters? Well, in those games, if you use the same letter more than once in the same word, it doesn't count. That's kind of like an isogram! It means the word only uses each letter once, so it's really special. It's like getting all the pieces of a puzzle to fit together perfectly without any overlaps or gaps. Can you think of any isograms? One example is "lollipop" because it has every letter in it only once. Cool, huh?