ELI5: Explain Like I'm 5

Machine perfusion

Hey there! Have you ever seen a plant that's been kept in water before it's planted in soil? That's kind of like machine perfusion, but instead of a plant, we're talking about organs from people or animals that are waiting to be transplanted into another body.

You see, when an organ is removed from a body, like a heart or a liver, it needs to be kept healthy and working until it can be transplanted into someone else who needs it. That's where machine perfusion comes in.

With machine perfusion, the organ is hooked up to a special machine that keeps it at the right temperature and pumps special fluids through it to make sure it stays healthy. It's like the machine is taking care of the organ until it's ready for its new home.

The pumping helps to keep the organ working by bringing oxygen and other important nutrients to the tissues, just like how our blood carries oxygen and nutrients to our body. This way, the organ is kept as healthy as possible until it can be transplanted.

Scientists and doctors are always looking for new and better ways to take care of organs before they're transplanted, and machine perfusion is one way they're doing that. By keeping the organs healthy, they have a better chance of working correctly when they're transplanted into their new body.
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