ELI5: Explain Like I'm 5

Microbial population biology

Microbial population biology is about studying microbes, which are tiny living things that are too small to see without a microscope.

Imagine you have a bunch of tiny cars, each with their own driver. These cars are like the microbes, and the drivers are like the genes that control how the microbes behave. Just like how different drivers can make the cars move in different ways, different genes can make the microbes behave differently.

Now imagine you have a big toy city, with lots of houses and streets. This city is like the environment that the microbes live in. Some of the houses and streets might be better suited for the cars to move on than others. Similarly, some environments might be better for certain microbes to grow and thrive in than others.

Scientists who study microbial population biology look at how different genes and environments affect the growth and behavior of microbes. They also look at how populations of microbes change over time, and how they adapt to new environments or situations.

For example, if you have a group of microbes that are all sensitive to a particular drug, and you start exposing them to that drug, you might end up with a population of microbes that have become resistant to the drug. This is because the microbes with genes that help them survive the drug will be the ones that are more likely to reproduce and pass on their genes to the next generation.

Overall, microbial population biology is a way of understanding how tiny living things interact with each other and their environment.