ELI5: Explain Like I'm 5

Nucleotide diversity

Nucleotide diversity is a fancy way of talking about the differences between DNA molecules. Think of nucleotide diversity like comparing different types of building blocks. Just like building blocks can be put together in different ways to make different structures, DNA molecules can also have slightly different building blocks that make them unique.

Nucleotides are the building blocks of DNA, just like how Legos are building blocks for toys. DNA is made up of four different types of nucleotides: adenine, thymine, guanine, and cytosine. These nucleotides help to spell out the genetic code that determines what makes each living thing unique.

Nucleotide diversity measures the amount of variation between different DNA molecules from different organisms, populations or individuals. For example, it can measure how similar or different the DNA of two different types of birds might be. By studying nucleotide diversity, scientists can learn more about how species evolve and adapt to their environments.

So, just like how comparing different Lego creations can tell you a lot about someone's building style, looking at nucleotide diversity can give scientists important information about the genetics of different organisms.