ELI5: Explain Like I'm 5

Quellung reaction

The quellung reaction is like a game of dress-up for tiny bacteria. Imagine you have a bunch of friends who all look the same, but you want to know who is who. So, you decide to give them all different outfits. That's what the quellung reaction does for bacteria.

But instead of outfits, we use tiny molecules called antibodies that stick to the bacteria in different ways. These antibodies act like a magnifying glass that helps us see the bacteria better.

So, we take a sample of bacteria and mix it with different antibodies. If the bacteria match up with the antibody, they'll look bigger and fatter, kind of like when you put on a hat that's too big for your head. This is called "positive" reaction. If the bacteria don't match up with the antibody, they'll look the same as before, and we call that a "negative" reaction.

This helps us figure out what kind of bacteria we're dealing with. It's like when you play dress-up, you can tell who is who because of what they're wearing. The quellung reaction just helps us dress up the bacteria.